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1

Disposition of the naturally occurring antimutagenic plant phenol, ellagic acid, and its synthetic derivatives, 3- O -decylellagic acid and 3, 3'-di- O -methylellagic acid in mice

Smart, Robert C., Huang, Mou-Tuan, Chang, Richard L., Sayer, Jane M., Jerina, Donald M., Conney, Allan H.

Journal:

Année:

1986

Langue:

english

Fichier:

PDF, 477 KB

english, 1986

2

Effect of ellagic acid and 3- O -decylellagic acid on the formation of benzo[ a ]pyrene-derived DNA adducts in vivo and on the tumorigenicity of 3-methylcholanthrene in mice

Smart, Robert C., Huang, Mou-Tuan, Chang, Richard L., Sayer, Jane M., Jerina, Donald M., Wood, Alexander W., Conney, Allan H.

Journal:

Année:

1986

Langue:

english

Fichier:

PDF, 684 KB

english, 1986

3

Anthracene 1,2-oxide: synthesis and role in the metabolism of anthracene by mammals

Akhtar, M. Naseem, Hamilton, James G., Boyd, Derek R., Braunstein, Alan, Seifried, Harold E., Jerina, Donald M.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1979

Langue:

english

Fichier:

PDF, 742 KB

english, 1979

4

ChemInform Abstract: New and Highly Efficient Synthesis of cis- and trans-Opened Benzo[a]pyrene 7,8-Diol 9,10-Epoxide Adducts at the Exocyclic N2-Amino Group of Deoxyguanosine.

Heiko Kroth, Haruhiko Yagi, Albrecht Seidel, Donald M. Jerina

Journal:

Année:

2000

Fichier:

PDF, 35 KB

2000

5

ChemInform Abstract: From Arene Oxides to Diol Epoxides and DNA

Donald M. Jerina

Journal:

Année:

2001

Fichier:

PDF, 24 KB

2001

6

ChemInform Abstract: New Insights on the Mechanisms of the pH-Independent Reactions of Benzo[a]pyrene 7,8-Diol 9,10-Epoxides.

Lanxuan Doan, Bin Lin, Haruhiko Yagi, Donald M. Jerina, Dale L. Whalen

Journal:

Année:

2001

Fichier:

PDF, 27 KB

2001

7

Specifically tritiated arene oxides

Haruhiko Yagi, Patrick Dansette, Donald M. Jerina

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

1976

Langue:

english

Fichier:

PDF, 272 KB

english, 1976

8

Synthesis of tritium labelled 7-dehydrocholesterol 5β,6β-oxide

Dennis P. Michaud, Nashaat T. Nashed, Donald M. Jerina

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

1986

Langue:

english

Fichier:

PDF, 235 KB

english, 1986

9

Nitrogen-15 coupling constants: Geminal coupling, 2J(15NH), in cis- and trans-aldonitrones and vicinal coupling, 3J(15NH), in cis-and trans-ketimines, oxaziridines and nitrones

Derek R. Boyd, Michael E. Stubbs, N. J. Thompson, Herman J. C. Yeh, Donald M. Jerina, Roderick E. Wasylishen

Journal:

Magnetic Resonance in Chemistry

Année:

1980

Langue:

english

Fichier:

PDF, 589 KB

english, 1980

10

Continuous fluorometric assay of epoxide hydrase activity

Patrick M. Dansette, Garrett C. DuBois, Donald M. Jerina

Journal:

Analytical Biochemistry

Année:

1979

Langue:

english

Fichier:

PDF, 478 KB

english, 1979

11

The absolute stereochemistry of several cis-dihydrodiols microbially produced from substituted benzenes

Herman Ziffer, Kuninbu Kabuto, D.T. Gibson, V.M. Kobal, Donald M. Jerina

Journal:

Année:

1977

Langue:

english

Fichier:

PDF, 587 KB

english, 1977

12

Photolysis of pyridine-N-oxide: an oxygen atom transfer model for enzymatic oxygenation, arene oxide formation, and the NIH shift

Donald M. Jerina, Derek R. Boyd, John W. Daly

Journal:

Tetrahedron Letters

Année:

1970

Langue:

english

Fichier:

PDF, 222 KB

english, 1970

13

Absolute configurations of the arene oxide, trans-dihydrodiol and cis-dihydeodiol products resulting from metabolism of quinoline at the 5,6-bond

Derek R. Boyd, Daniel R. Bushman, R.Jeremy H. Davies, Michael R.J. Dorriy, Lynne Hamilton, Donald M. Jerina, Wayne Levin, John J. McCullough, R.Austin S. McMordie, John F. Malone, H.Patricia Porter

Journal:

Tetrahedron Letters

Année:

1991

Langue:

english

Fichier:

PDF, 266 KB

english, 1991

14

Effect of salt on the kinetic parameters of retroviral and mammalian aspartic acid proteases

Joseph E. Tropea, Nashaat T. Nashed, John M. Louis, Jane M. Sayer, Donald M. Jerina

Journal:

Bioorganic Chemistry

Année:

1992

Langue:

english

Fichier:

PDF, 770 KB

english, 1992

15

Analysis of human topoisomerase I inhibition and interaction with the cleavage site +1 deoxyguanosine, via in vitro experiments and molecular modeling studies

Gary S. Laco, Wu Du, Glenda Kohlhagen, Jane M. Sayer, Donald M. Jerina, Thomas G. Burke, Dennis P. Curran, Yves Pommier

Journal:

Bioorganic & Medicinal Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 597 KB

english, 2004

16

Synthesis of monofluorobenzo[c]phenanthrenes

Yitzhak Ittah, Donald M. Jerina

Journal:

Journal of Fluorine Chemistry

Année:

1980

Langue:

english

Fichier:

PDF, 394 KB

english, 1980

17

Novel trifluoroethanol mediated synthesis of benzo[a]pyrene 7,8-diol 9,10-epoxide adducts at the N2-position of deoxyguanosine and the N6-position of deoxyadenosine

Andagar R Ramesha, Heiko Kroth, Donald M Jerina

Journal:

Tetrahedron Letters

Année:

2001

Langue:

english

Fichier:

PDF, 74 KB

english, 2001

18

Synthesis of deoxyadenosine adducts from the highly carcinogenic fjord region diol epoxide of benzo[c]phenanthrene

Mahesh K. Lakshman, Herman J.C. Yeh, Haruhiko Yagi, Donald M. Jerina

Journal:

Tetrahedron Letters

Année:

1992

Langue:

english

Fichier:

PDF, 320 KB

english, 1992

19

Aza-polycyclic aromatic hydrocarbon carcinogenicity: predictions of reactivity of tetrahydrobenzo ring epoxide derivatives

Roland E. Lehr, Donald M. Jerina

Journal:

Tetrahedron Letters

Année:

1983

Langue:

english

Fichier:

PDF, 250 KB

english, 1983

20

Resolution and assignement of absolute configuration to the (+)- and (−)-cis and trans 3,4-diol metabolites of the anti-juvenile hormone precocene I

Rita A. Halpin, Shaaban F. El-Naggar, Kenneth M. McCombe, Kamlesh P. Vyas, Derek R. Boyd, Donald M. Jerina

Journal:

Tetrahedron Letters

Année:

1982

Langue:

english

Fichier:

PDF, 266 KB

english, 1982

21

Epoxide and diol epoxide adducts of polycyclic aromatic hydrocarbons at the exocyclic amino group of deoxyguanosine

Barbara Zajc, Mahesh K. Lakshman, Jane M. Sayer, Donald M. Jerina

Journal:

Tetrahedron Letters

Année:

1992

Langue:

english

Fichier:

PDF, 321 KB

english, 1992

22

Brunfelsamidine: a novel convulsant from the medicinal plant brunfelsia grandiflora

Helen A. Lloyd, Henry M. Fales, Mark E. Goldman, Donald M. Jerina, Timothy Plowman, Richard E. Schultes

Journal:

Tetrahedron Letters

Année:

1985

Langue:

english

Fichier:

PDF, 149 KB

english, 1985

23

Synthesis and reactivity of diol epoxides derived from non-K-region trans-dihydrodiols of benzo[a]anthracene

Roland E. Lehr, Maria Schaefer-Ridder, Donald M. Jerina

Journal:

Tetrahedron Letters

Année:

1977

Langue:

english

Fichier:

PDF, 228 KB

english, 1977

24

Synthesis of (+)- and (−)-benzo[a]pyrene 7,8-oxide

Derek R. Boyd, Guru S. Gadaginamath, Robert Hamilton, Haruhiko Yagi, Donald M. Jerina

Journal:

Tetrahedron Letters

Année:

1978

Langue:

english

Fichier:

PDF, 227 KB

english, 1978

25

Cyclopenta[c,d]pyrene

Yitzhak Ittah, Donald M. Jerina

Journal:

Tetrahedron Letters

Année:

1978

Langue:

english

Fichier:

PDF, 237 KB

english, 1978

26

Dihydrodiols and diol epoxides of dibenzo[a,i]-and [a,h]pyrene

Roland E. Lehr, Subodh Kumar, Patrick T. Cohenour, Donald M. Jerina

Journal:

Tetrahedron Letters

Année:

1979

Langue:

english

Fichier:

PDF, 276 KB

english, 1979

27

Catalytic aminohydroxylation using adenine-derivatives as the nitrogen source

K.Ruprecht Dress, Lukas J. Gooßen, Hong Liu, Donald M. Jerina, K.Barry Sharpless

Journal:

Tetrahedron Letters

Année:

1998

Langue:

english

Fichier:

PDF, 238 KB

english, 1998

28

Incorporation of 4-thiothymidine into DNA by the klenow fragment and HIV-1 reverse transcriptase

Tata Venkata S Rao, Martin T Haber, Jane M Sayer, Donald M Jerina

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2000

Langue:

english

Fichier:

PDF, 127 KB

english, 2000

29

Enantiomeric Composition of Trans-Dihydrodiols Formed from Meso-K-Region Arene Oxides by Microsomal Epoxide Hydrolase

Martin T. Haber, Nashaat T. Nashed, Donald M. Jerina

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1992

Langue:

english

Fichier:

PDF, 490 KB

english, 1992

30

Metabolic activations of polycyclic hydrocarbons

Roland E. Lehr, Donald M. Jerina

Journal:

Archives of Toxicology

Année:

1977

Langue:

english

Fichier:

PDF, 340 KB

english, 1977

31

Benzo[a]pyrene 7,8-dihydrodiol is more carcinogenic than benzo[a]pyrene in newborn mice

KAPITULNIK, JAIME, LEVIN, WAYNE, CONNEY, ALLAN H., YAGI, HARUHIKO, JERINA, DONALD M.

Journal:

Année:

1977

Fichier:

PDF, 326 KB

1977

32

Changes of mechanisms and product distributions in the hydrolysis of benzo[a]pyrene-7,8-diol 9,10,-epoxide metabolites induced by changes in pH

Whalen, Dale L., Montemarano, Jean A., Thakker, Dhiren R., Yagi, Haruhiko, Jerina, Donald M.

Journal:

Journal of the American Chemical Society

Année:

1977

Langue:

english

Fichier:

PDF, 378 KB

english, 1977

33

Induction, activation and inhibition of epoxide hydrase: an anomalous prevention of chlorobenzene-induced hepatotoxicity by an inhibitor of epoxide hydrase

Franz Oesch, Donald M. Jerina, John W. Daly, Jerry M. Rice

Journal:

Chemico-Biological Interactions

Année:

1973

Langue:

english

Fichier:

PDF, 1.08 MB

english, 1973

34

Postreplication repair of DNA in human fibroblasts after UV irradiation or treatment with metabolites of benzo(a)pyrene

Raymond Waters, H. Yagi, Donald M. Jerina, James D. Regan

Journal:

Chemico-Biological Interactions

Année:

1978

Langue:

english

Fichier:

PDF, 486 KB

english, 1978

35

Repair of DNA damaged by mutagenic metabolites of benzo(a)pyrene in human cells

James D. Regan, A.A. Francis, W.C. Dunn, O. Hernandez, H. Yagi, Donald M. Jerina

Journal:

Chemico-Biological Interactions

Année:

1978

Langue:

english

Fichier:

PDF, 503 KB

english, 1978

36

Metabolism and hepatotoxicity of the naturally occurring benzo[b]pyran precocene I

Rita A. Halpin, Kamlesh P. Vyas, Shaaban F. El-Naggar, Donald M. Jerina

Journal:

Chemico-Biological Interactions

Année:

1984

Langue:

english

Fichier:

PDF, 1.44 MB

english, 1984

37

Stereo-selectivity and regio-selectivity in the metabolism of 7,8-dihydrobenzo[a]pyrene by cytochrome P450, epoxide hydrolase and hepatic microsomes from 3-methylcholanthrene-treated rats

James D. Adams Jr., Haruhiko Yagi, Wayne Levin, Donald M. Jerina

Journal:

Chemico-Biological Interactions

Année:

1995

Langue:

english

Fichier:

PDF, 1.58 MB

english, 1995

38

The proximate carcinogen trans-3,4-dihydroxy-3,4-dihydro-dibenz[c,h]acridine is oxidized stereoselectively and regioselectively by cytochrome 1A1, epoxide hydrolase and hepatic microsomes from 3-methylcholanthrene-treated rats

James D Adams Jr, Jane M Sayer, Anju Chadha, Naohiro Shirai, Roland E Lehr, Subodh Kumar, Donald M Jerina

Journal:

Chemico-Biological Interactions

Année:

1999

Langue:

english

Fichier:

PDF, 180 KB

english, 1999

39

Benzo[a]pyrene diol epoxide–deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase ζ in vitro

Srilatha Simhadri, Pavel Kramata, Barbara Zajc, Jane M. Sayer, Donald M. Jerina, David C. Hinkle, Caroline S.-J. Wei

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

2002

Langue:

english

Fichier:

PDF, 180 KB

english, 2002

40

Erratum to “Benzo[a]pyrene diol epoxide–deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase ζ in vitro” [Mutat. Res. 508 (2002) 137–145]

Srilatha Simhadri, Pavel Kramata, Barbara Zajc, Jane M. Sayer, Donald M. Jerina, David C. Hinkle, Caroline S.-J. Wei

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

2003

Langue:

english

Fichier:

PDF, 30 KB

english, 2003

41

The Mechanism of Action of Cytochrome P-450. Occurrence of the ‘NIH Shift’ during Hydroperoxide-Dependent Aromatic Hydroxylations

Anver D. RAHIMTULA, Peter J. O'BRIEN, Harold E. SEIFRIED, Donald M. JERINA

Journal:

Année:

1978

Langue:

english

Fichier:

PDF, 859 KB

english, 1978

42

Autoprocessing of the HIV-1 protease using purified wild-type and mutated fusion proteins expressed at high levels in Escherichia coli

John M. LOUIS, Richard A. McDONALD, Nashaat T. NASHED, Ewald M. WONDRAK, Donald M. JERINA, Stephen OROSZLAN, Peter T. MORA

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 1.36 MB

english, 1991

43

Cis-1,2-dihydroxy-1,2-dihydronaphthalene: A bacterial metabolite from naphthalene

Donald M. Jerina, John W. Daly, Alan M. Jeffrey, David T. Gibson

Journal:

Archives of Biochemistry and Biophysics

Année:

1971

Langue:

english

Fichier:

PDF, 197 KB

english, 1971

44

Substrate specificity of hepatic epoxide hydrase in microsomes and in a purified preparation: Evidence for homologous enzymes

Franz Oesch, Donald M. Jerina, John W. Daly

Journal:

Archives of Biochemistry and Biophysics

Année:

1971

Langue:

english

Fichier:

PDF, 734 KB

english, 1971

45

Substrates and inhibitors of hepatic glutathione-S-epoxide transferase

Taro Hayakawa, Sidney Udenfriend, Haruhiko Yagi, Donald M. Jerina

Journal:

Archives of Biochemistry and Biophysics

Année:

1975

Langue:

english

Fichier:

PDF, 843 KB

english, 1975

46

Metabolism of benzo[a]pyrene: Effect of 3-methylcholanthrene pretreatment on metabolism by microsomes from lungs of genetically “responsive” and ”nonresponsive” mice

Harold E. Seifried, Donald J. Birkett, Wayne Levin, Anthony Y.H. Lu, Allan H. Conney, Donald M. Jerina

Journal:

Archives of Biochemistry and Biophysics

Année:

1977

Langue:

english

Fichier:

PDF, 713 KB

english, 1977

47

Mechanism of catalysis for the hydration of substituted styrene oxides by hepatic epoxide hydrase

Patrick M. Dansette, Vanya B. Makedonska, Donald M. Jerina

Journal:

Archives of Biochemistry and Biophysics

Année:

1978

Langue:

english

Fichier:

PDF, 784 KB

english, 1978

48

Properties of liver microsomal cholesterol 5,6-oxide hydrolase

Nashaat T. Nashed, Dennis P. Michaud, Wayne Levin, Donald M. Jerina

Journal:

Archives of Biochemistry and Biophysics

Année:

1985

Langue:

english

Fichier:

PDF, 1.19 MB

english, 1985

49

Novel stereoselectivity of rat liver cytochrome(s) P450 toward enantiomers of the trans-1,2-dihydrodiol of triphenylene

Dhiren R. Thakker, Charles Boehlert, Wayne Levin, Dene E. Ryan, Paul E. Thomas, Haruhiko Yagi, Donald M. Jerina

Journal:

Archives of Biochemistry and Biophysics

Année:

1991

Langue:

english

Fichier:

PDF, 1.03 MB

english, 1991

50

Absolute configuration of the 5,6-oxide formed from 7,12-dimethylbenz[a]anthracene by cytochrome P450c

Suresh K. Balani, Herman J.C. Yeh, Dene E. Ryan, Paul E. Thomas, Wayne Levin, Donald M. Jerina

Journal:

Biochemical and Biophysical Research Communications

Année:

1985

Langue:

english

Fichier:

PDF, 461 KB

english, 1985